High-Throughput Genotyping in Metastatic Esophageal Squamous Cell Carcinoma Identifies Phosphoinositide-3-Kinase and BRAF Mutations

BACKGROUND: Given the high incidence of metastatic esophageal squamous cell carcinoma, especially in Asia, we screened for the presence of somatic mutations using OncoMap platform with the aim of defining subsets of patients who may be potential candidate for targeted therapy. METHODS AND MATERIALS:...

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Detalhes bibliográficos
Main Authors: Maeng, Chi Hoon, Lee, Jeeyun, van Hummelen, Paul, Park, Se Hoon, Palescandolo, Emanuele, Jang, Jiryeon, Park, Ha Young, Kang, So Young, MacConaill, Laura, Kim, Kyoung-Mee, Shim, Young-Mog
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411721/
https://ncbi.nlm.nih.gov/pubmed/22870241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041655
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