Differential Effects of Cystathionine-γ-lyase–Dependent Vasodilatory H(2)S in Periadventitial Vasoregulation of Rat and Mouse Aortas

BACKGROUND: Hydrogen sulfide (H(2)S) is a potent vasodilator. However, the complex mechanisms of vasoregulation by H(2)S are not fully understood. We tested the hypotheses that (1) H(2)S exerts vasodilatory effects by opening KCNQ-type voltage-dependent (K(v)) K(+) channels and (2) that H(2)S-produc...

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Main Authors: Köhn, Carolin, Schleifenbaum, Johanna, Szijártó, István András, Markó, Lajos, Dubrovska, Galyna, Huang, Yu, Gollasch, Maik
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411702/
https://ncbi.nlm.nih.gov/pubmed/22870268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041951
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