Survivin Is Required for Beta-Cell Mass Expansion in the Pancreatic Duct-Ligated Mouse Model

AIMS/HYPOTHESIS: Pancreatic beta-cell mass expands through adulthood under certain conditions. The related molecular mechanisms are elusive. This study was designed to determine whether surviving (also known as Birc5), which is transiently expressed perinatally in islets, was required for beta-cell...

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Главные авторы: Wu, Xiaohong, Zhang, Qinfeng, Wang, Xiaojing, Zhu, Jiayu, Xu, Kuangfeng, Okada, Hitoshi, Wang, Rennian, Woo, Minna
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411579/
https://ncbi.nlm.nih.gov/pubmed/22870272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041976
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