Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

BACKGROUND: In brain tissues from multiple sclerosis (MS) patients, clusters of activated HLA-DR-expressing microglia, also referred to as preactive lesions, are located throughout the normal-appearing white matter. The aim of this study was to gain more insight into the frequency, distribution and...

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Bibliografische gegevens
Hoofdauteurs: van Horssen, Jack, Singh, Shailender, van der Pol, Susanne, Kipp, Markus, Lim, Jamie L, Peferoen, Laura, Gerritsen, Wouter, Kooi, Evert-Jan, Witte, Maarten E, Geurts, Jeroen JG, de Vries, Helga E, Peferoen-Baert, Regina, van den Elsen, Peter J, van der Valk, Paul, Amor, Sandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411485/
https://ncbi.nlm.nih.gov/pubmed/22747960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-156
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