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Selenium preserves mitochondrial function, stimulates mitochondrial biogenesis, and reduces infarct volume after focal cerebral ischemia

BACKGROUND: Mitochondrial dysfunction is one of the major events responsible for activation of neuronal cell death pathways during cerebral ischemia. Trace element selenium has been shown to protect neurons in various diseases conditions. Present study is conducted to demonstrate that selenium prese...

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Bibliografiske detaljer
Main Authors: Mehta, Suresh L, Kumari, Santosh, Mendelev, Natalia, Li, P Andy
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411431/
https://ncbi.nlm.nih.gov/pubmed/22776356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-79
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