A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells

Embryonic definitive endoderm (DE) generates the epithelial compartment of vital organs such as liver, pancreas, and intestine. However, purification of DE in mammals has not been achieved, limiting the molecular “definition” of endoderm, and hindering our understanding of DE development and attempt...

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Autores principales: Wang, Pei, McKnight, Kristen D., Wong, David J., Rodriguez, Ryan T., Sugiyama, Takuya, Gu, Xueying, Ghodasara, Amar, Qu, Kun, Chang, Howard Y., Kim, Seung K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
Materias:
Original Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411363/
https://ncbi.nlm.nih.gov/pubmed/22236333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0416
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