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Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates
14-3-3 proteins regulate cellular responses to stimuli by docking onto pairs of phosphorylated residues on target proteins. The present study shows that the human 14-3-3-binding phosphoproteome is highly enriched in 2R-ohnologues, which are proteins in families of two to four members that were gener...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411107/ https://ncbi.nlm.nih.gov/pubmed/22870394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.120103 |
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