Function of GRIM-19, a Mitochondrial Respiratory Chain Complex I Protein, in Innate Immunity

Mitochondria respiratory chain (RC), consisting of five multisubunit complexes, is crucial for cellular energy production, reactive oxygen species generation, and regulation of apoptosis. Recently, a few mitochondrial proteins have been reported to be essential for innate immunity, but the function...

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Main Authors: Chen, Yong, Lu, Hao, Liu, Qian, Huang, Guochang, Lim, Cheh Peng, Zhang, Lianhui, Hao, Aijun, Cao, Xinmin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411064/
https://ncbi.nlm.nih.gov/pubmed/22665480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340315
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