Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter

Nucleophosmin (NPM1) is a nucleocytoplasmic shuttling protein, mainly localized at nucleoli, that plays a key role in several cellular functions, including ribosome maturation and export, centrosome duplication, and response to stress stimuli. More than 50 mutations at the terminal exon of the NPM1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gallo, Angelo, Lo Sterzo, Carlo, Mori, Mirko, Di Matteo, Adele, Bertini, Ivano, Banci, Lucia, Brunori, Maurizio, Federici, Luca
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410995/
https://ncbi.nlm.nih.gov/pubmed/22707729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371013
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