Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction

The genetic loci that have been found by genome-wide association studies to modulate risk of coronary heart disease explain only a fraction of its total variance, and gene-gene interactions have been proposed as a potential source of the remaining heritability. Given the potentially large testing bu...

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Detalhes bibliográficos
Main Authors: Lucas, Gavin, Lluís-Ganella, Carla, Subirana, Isaac, Musameh, Muntaser D., Gonzalez, Juan Ramon, Nelson, Christopher P., Sentí, Mariano, Schwartz, Stephen M., Siscovick, David, O’Donnell, Christopher J., Melander, Olle, Salomaa, Veikko, Purcell, Shaun, Altshuler, David, Samani, Nilesh J., Kathiresan, Sekar, Elosua, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410908/
https://ncbi.nlm.nih.gov/pubmed/22876292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041730
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