Disruption of the folate pathway in zebrafish causes developmental defects

BACKGROUND: Folic acid supplementation reduces the risk of neural tube defects and congenital heart defects. The biological mechanisms through which folate prevents birth defects are not well understood. We explore the use of zebrafish as a model system to investigate the role of folate metabolism d...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Lee, Marina S, Bonner, Jenna R, Bernard, David J, Sanchez, Erica L, Sause, Eric T, Prentice, R Reid, Burgess, Shawn M, Brody, Lawrence C
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410756/
https://ncbi.nlm.nih.gov/pubmed/22480165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-12-12
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