Cryptotanshinone Activates p38/JNK and Inhibits Erk1/2 Leading to Caspase-Independent Cell Death in Tumor Cells

Cryptotanshinone (CPT), a natural compound isolated from the plant Salvia miltiorrhiza Bunge, is a potential anticancer agent. However, the underlying mechanism is not well understood. Here, we show that CPT induced caspase-independent cell death in human tumor cells (Rh30, DU145, and MCF-7). Beside...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chen, Wenxing, Liu, Lei, Luo, Yan, Odaka, Yoshinobu, Awate, Sanket, Zhou, Hongyu, Shen, Tao, Zheng, Shizhong, Lu, Yin, Huang, Shile
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410745/
https://ncbi.nlm.nih.gov/pubmed/22490436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0551
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky