Genotype Imputation of Metabochip SNPs Using a Study-Specific Reference Panel of ~4,000 Haplotypes in African Americans From the Women’s Health Initiative

Genetic imputation has become standard practice in modern genetic studies. However, several important issues have not been adequately addressed including the utility of study-specific reference, performance in admixed populations, and quality for less common (minor allele frequency [MAF] 0.005–0.05)...

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書誌詳細
主要な著者: Liu, Eric Yi, Buyske, Steven, Aragaki, Aaron K., Peters, Ulrike, Boerwinkle, Eric, Carlson, Chris, Carty, Cara, Crawford, Dana C., Haessler, Jeff, Hindorff, Lucia A., Marchand, Loic Le, Manolio, Teri A., Matise, Tara, Wang, Wei, Kooperberg, Charles, North, Kari E., Li, Yun
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410659/
https://ncbi.nlm.nih.gov/pubmed/22851474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21603
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