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Rapid Testing of Gene-Gene Interactions in Genome-Wide Association Studies of Binary and Quantitative Phenotypes

Genome-wide association (GWA) studies have been extremely successful in identifying novel loci contributing effects to a wide range of complex human traits. However, despite this success, the joint marginal effects of these loci account for only a small proportion of the heritability of these traits...

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Hlavní autoři: Bhattacharya, Kanishka, McCarthy, Mark I, Morris, Andrew P
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410530/
https://ncbi.nlm.nih.gov/pubmed/21948692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20629
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