Silencing of anti-apoptotic transmembrane protein lifeguard sensitizes solid tumor cell lines MCF-7 and SW872 to perifosine-induced cell death activation

Lifeguard (LFG), an anti-apoptotic protein with high expression rates in breast cancer cells, has been identified as a molecule that inhibits death mediated by Fas. The molecular function of LFG and its regulation in the carcinogenesis of human breast and sarcoma cells, however, remains to be elucid...

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Main Authors: BUCAN, VESNA, CHOI, CLAUDIA Y.U., LAZARIDIS, ANDREA, VOGT, PETER M., REIMERS, KERSTIN
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410496/
https://ncbi.nlm.nih.gov/pubmed/22866097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.285
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