Effect of Arthritic Synovial Fluids on the Expression of Immunomodulatory Factors by Mesenchymal Stem Cells: An Explorative in vitro Study

Background: In diseased joints, the catabolic environment results in progressive joint damage. Mesenchymal stem cells (MSCs) can have immunomodulatory effects by secreting anti-inflammatory factors. To exert these effects, MSCs need to be triggered by pro-inflammatory cytokines. To explore the poten...

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Main Authors: Leijs, Maarten J. C., van Buul, Gerben M., Lubberts, Erik, Bos, Pieter K., Verhaar, Jan A. N., Hoogduijn, Martin J., van Osch, Gerjo J. V. M.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410447/
https://ncbi.nlm.nih.gov/pubmed/22876244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00231
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