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Unraveling A Trap-and-Trigger Mechanism in the pH-Sensitive Self-Assembly of Spider Silk Proteins

When the major ampulate spidroins (MaSp1) are called upon to form spider dragline silk, one of nature’s most amazing materials, a small drop in pH must occur. Using a state-of-the-art simulation technique, constant pH molecular dynamics, we discovered a few residues that respond to the pH signal in...

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Detalhes bibliográficos
Main Authors: Wallace, Jason A., Shen, Jana K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410443/
https://ncbi.nlm.nih.gov/pubmed/22866209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz2016846
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