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Solid-phase synthesis of the self-complementary hexamer d(c7GpCpc7GpCpc7GpC) via the O-3'-phosphoramidite of 7-deaza-2'-deoxyguanosine.

The synthesis of the O-3'-phosphoramidite of a suitably protected 7-deaza-2'-deoxyguanosine (c7G) which is an isostere of 2'-deoxyguanosine is described. The phosphoramidite of the modified nucleoside was used in the synthesis of the self-complementary hexamer d(c7GpCpc7GpCpc7GpC) on...

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Detalhes bibliográficos
Main Authors: Seela, F, Driller, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC341042/
https://ncbi.nlm.nih.gov/pubmed/4000931
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