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Class II formin targeting to the cell cortex by binding PI(3,5)P(2) is essential for polarized growth

Class II formins are key regulators of actin and are essential for polarized plant cell growth. Here, we show that the class II formin N-terminal phosphatase and tensin (PTEN) domain binds phosphoinositide-3,5-bisphosphate (PI(3,5)P(2)). Replacing the PTEN domain with polypeptides of known lipid-bin...

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Sonraí Bibleagrafaíochta
Main Authors: van Gisbergen, Peter A.C., Li, Ming, Wu, Shu-Zon, Bezanilla, Magdalena
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410418/
https://ncbi.nlm.nih.gov/pubmed/22801781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112085
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