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Class II formin targeting to the cell cortex by binding PI(3,5)P(2) is essential for polarized growth

Class II formins are key regulators of actin and are essential for polarized plant cell growth. Here, we show that the class II formin N-terminal phosphatase and tensin (PTEN) domain binds phosphoinositide-3,5-bisphosphate (PI(3,5)P(2)). Replacing the PTEN domain with polypeptides of known lipid-bin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Gisbergen, Peter A.C., Li, Ming, Wu, Shu-Zon, Bezanilla, Magdalena
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410418/
https://ncbi.nlm.nih.gov/pubmed/22801781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112085
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