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Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase

Influenza A continues to be a major public health concern due to its ability to cause epidemic and pandemic disease outbreaks in humans. Computational investigations of structural dynamics of the major influenza glycoproteins, especially the neuraminidase (NA) enzyme, are able to provide key insight...

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Detalhes bibliográficos
Main Authors: Votapka, Lane, Demir, Özlem, Swift, Robert V, Walker, Ross C, Amaro, Rommie E
Formato: Artigo
Idioma:Inglês
Publicado em: Library Publishing Media 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410406/
https://ncbi.nlm.nih.gov/pubmed/22872804
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