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Distinct roles for direct and indirect pathway striatal neurons in reinforcement

Dopamine signaling is implicated in reinforcement learning, but the neural substrates targeted by dopamine are poorly understood. Here, we bypassed dopamine signaling itself and tested how optogenetic activation of dopamine D1- or D2-receptor-expressing striatal projection neurons influenced reinfor...

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Bibliographic Details
Main Authors: Kravitz, Alexxai V., Tye, Lynne D., Kreitzer, Anatol C.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410042/
https://ncbi.nlm.nih.gov/pubmed/22544310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3100
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