Chromosomal orientation of the lambda light chain locus: V lambda is proximal to C lambda in 22q11.
We have demonstrated that the chromosomal breakpoint at 22q11 of a Burkitt lymphoma cell line (PA682) with an 8;22 translocation interrupts the variable region of the lambda light chain locus. In these cells, all of the C lambda and some V lambda sequences translocate to the 8q+ chromosome whereas s...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1985
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3923432/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.2.381 |
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