The Aurora A and B kinases are up-regulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets

BACKGROUND: The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and the pathways that propagate them to the interior of the cell is important for...

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Detalhes bibliográficos
Main Authors: de Paula Careta, Francisco, Gobessi, Stefania, Panepucci, Rodrigo Alexandre, Bojnik, Engin, Morato de Oliveira, Fabio, Mazza Matos, Daniel, Falcão, Roberto P., Laurenti, Luca, Zago, Marco A., Efremov, Dimitar G.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409824/
https://ncbi.nlm.nih.gov/pubmed/22331265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.054668
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