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Gla-domainless factor Xa: molecular bait to bypass a blocked tenase complex
BACKGROUND: Hemophilia is caused by deficiencies in coagulation factor VIII or IX, resulting in direct blockade of the intrinsic tenase complex and indirect blockade of the extrinsic tenase complex which is rapidly inhibited upon binding of factor Xa to tissue factor pathway inhibitor. We evaluated...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ferrata Storti Foundation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409813/ https://ncbi.nlm.nih.gov/pubmed/22491732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.055699 |
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