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Interleukin-1R3 mediates interleukin-1–induced potassium current increase through fast activation of Akt kinase

Inflammatory cytokine interleukin-1 (IL-1) performs multiple functions in the central nervous system. The type 1 IL-1 receptor (IL-1R1) and the IL-1 receptor accessory protein (IL-1RAcP) form a functional IL-1 receptor complex that is thought to mediate most, if not all, IL-1–induced effects. Severa...

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Detalhes bibliográficos
Main Authors: Qian, Jiang, Zhu, Ling, Li, Qiming, Belevych, Natalya, Chen, Qun, Zhao, Fangli, Herness, Scott, Quan, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409776/
https://ncbi.nlm.nih.gov/pubmed/22778412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205207109
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