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Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses

A coordinated innate and adaptive immune response, orchestrated by antigen presenting cells (APCs), is required for effective clearance of influenza A virus (IAV). Although IAV primarily infects epithelial cells of the upper respiratory tract, APCs are also susceptible. To determine if virus transcr...

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Detalhes bibliográficos
Main Authors: Langlois, Ryan A., Varble, Andrew, Chua, Mark A., García-Sastre, Adolfo, tenOever, Benjamin R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409765/
https://ncbi.nlm.nih.gov/pubmed/22778433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206039109
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