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Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron

Inositol hexakisphosphate (InsP(6)) levels rise and fall with neuronal excitation and silence, respectively, in the hippocampus, suggesting potential signaling functions of this inositol polyphosphate in hippocampal neurons. We now demonstrate that intracellular application of InsP(6) caused a conce...

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Detalhes bibliográficos
Main Authors: Yang, Shao-Nian, Shi, Yue, Yang, Guang, Li, Yuxin, Yu, Lina, Shin, Ok-Ho, Bacaj, Taulant, Südhof, Thomas C., Yu, Jia, Berggren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409763/
https://ncbi.nlm.nih.gov/pubmed/22778403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115070109
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