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Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals

During Mycobacterium tuberculosis infection, a population of bacteria likely becomes refractory to antibiotic killing in the absence of genotypic resistance, making treatment challenging. We describe an in vitro model capable of yielding a phenotypically antibiotic-tolerant subpopulation of cells, o...

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Detalhes bibliográficos
Main Authors: Grant, Sarah Schmidt, Kaufmann, Benjamin B., Chand, Nikhilesh S., Haseley, Nathan, Hung, Deborah T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409745/
https://ncbi.nlm.nih.gov/pubmed/22778419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203735109
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