Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice

The intestinal microbiota contributes to the development of the immune system, and conversely, the immune system influences the composition of the microbiota. Toll-like receptors (TLRs) in the gut recognize bacterial ligands. Although TLR signaling represents a major arm of the innate immune system,...

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Main Authors: Ubeda, Carles, Lipuma, Lauren, Gobourne, Asia, Viale, Agnes, Leiner, Ingrid, Equinda, Michele, Khanin, Raya, Pamer, Eric G.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409501/
https://ncbi.nlm.nih.gov/pubmed/22826298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120504
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