CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation

Alterations to blood-brain barrier (BBB) adhesion molecules and junctional integrity during neuroinflammation can promote central nervous system (CNS) pathology. The chemokine CCL2 is elevated during CNS inflammation and is associated with endothelial dysfunction. The effects of CCL2 on endothelial...

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Autores principales: Roberts, Toni K., Eugenin, Eliseo A., Lopez, Lillie, Romero, Ignacio A., Weksler, Babette B., Couraud, Pierre-Olivier, Berman, Joan W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409314/
https://ncbi.nlm.nih.gov/pubmed/22641100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2012.80
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