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A-to-I editing of microRNAs in the mammalian brain increases during development

Adenosine-to-inosine (A-to-I) RNA editing targets double-stranded RNA stem–loop structures in the mammalian brain. It has previously been shown that miRNAs are substrates for A-to-I editing. For the first time, we show that for several definitions of edited miRNA, the level of editing increases with...

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Autors principals: Ekdahl, Ylva, Farahani, Hossein Shahrabi, Behm, Mikaela, Lagergren, Jens, Öhman, Marie
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409261/
https://ncbi.nlm.nih.gov/pubmed/22645261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.131912.111
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