STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation

Malignant gliomas, including glioblastoma multiforme, constitute the most common and aggressive primary brain tumors in adults. The transcription factor signal transducer and activator of transcription 3 (STAT3) plays an essential role in glioblastoma pathogenesis downstream of the major oncogenic p...

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Detalhes bibliográficos
Main Authors: Puram, Sidharth V., Yeung, Caleb M., Jahani-Asl, Arezu, Lin, Chieyu, de la Iglesia, Nuria, Konopka, Genevieve, Jackson-Grusby, Laurie, Bonni, Azad
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409246/
https://ncbi.nlm.nih.gov/pubmed/22674257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3243-11.2012
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