Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production

Consumption of L-arginine contributes to reduced bioavailability of nitric oxide (NO) that is critical for the development of ischemia-reperfusion injury. The aim of the study was to determine myocardial arginase expression and activity in ischemic-reperfusion myocardium and whether local inhibition...

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Detalhes bibliográficos
Main Authors: Gonon, Adrian T., Jung, Christian, Katz, Abram, Westerblad, Håkan, Shemyakin, Alexey, Sjöquist, Per-Ove, Lundberg, Jon O., Pernow, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409239/
https://ncbi.nlm.nih.gov/pubmed/22860052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042038
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