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Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin
Sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), NAD(+)-dependent enzymes, link cellular energy status with responses to environmental stresses. Skin is frequently exposed to the DNA damaging effects of UV irradiation, a known etiology in skin cancer. Thus, understanding the defense mechan...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409181/ https://ncbi.nlm.nih.gov/pubmed/22860104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042276 |
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