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Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis

Visceral leishmaniasis (VL) caused by the intracellular parasite Leishmania donovani accounts for an estimated 12 million cases of human infection. It is almost always associated with anemia, which severely complicates the disease course. However, the pathological processes leading to anemia in VL h...

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Detalhes bibliográficos
Main Authors: Samanta, Sajal, Ghoshal, Angana, Bhattacharya, Kaushik, Saha, Bibhuti, Walden, Peter, Mandal, Chitra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409180/
https://ncbi.nlm.nih.gov/pubmed/22860118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042361
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