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Luminal Ca(2+) controls activation of the cardiac ryanodine receptor by ATP

The synergic effect of luminal Ca(2+), cytosolic Ca(2+), and cytosolic adenosine triphosphate (ATP) on activation of cardiac ryanodine receptor (RYR2) channels was examined in planar lipid bilayers. The dose–response of RYR2 gating activity to ATP was characterized at a diastolic cytosolic Ca(2+) co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tencerová, Barbora, Zahradníková, Alexandra, Gaburjáková, Jana, Gaburjáková, Marta
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409101/
https://ncbi.nlm.nih.gov/pubmed/22851674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110708
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