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Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore–quencher pairing
Voltage-activated proteins can sense, and respond to, changes in the electric field pervading the cell membrane by virtue of a transmembrane helix bundle, the voltage-sensing domain (VSD). Canonical VSDs consist of four transmembrane helices (S1–S4) of which S4 is considered a principal component be...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409098/ https://ncbi.nlm.nih.gov/pubmed/22802360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210807 |
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