Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma

MicroRNA (miRs) have emerged as salient regulators in cancer homeostasis and, recently, as putative therapeutics. Cholangiocarcinomas (CCA) are aggressive cancers with survival usually measured in months. mRNA arrays followed by pathway analysis revealed that miR-494 is a major modulator of the cell...

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Autores principales: Yamanaka, Sumitaka, Campbell, Nathaniel R., An, Fangmei, Kuo, Scot C., Potter, James J., Mezey, Esteban, Maitra, Anirban, Selaru, Florin M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409013/
https://ncbi.nlm.nih.gov/pubmed/22785131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21105
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