Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

Following acute hepatic injury, the metabolic capacity of the liver is altered during the process of compensatory hepatocyte proliferation by undefined mechanisms. In this study, we examined the regulation of de novo lipogenesis by cyclin D1, a key mediator of hepatocyte cell cycle progression. In p...

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Main Authors: Hanse, Eric A., Mashek, Douglas G., Becker, Jennifer R., Solmonson, Ashley D., Mullany, Lisa K., Mashek, Mara T., Towle, Howard C., Chau, Anhtung T., Albrecht, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409010/
https://ncbi.nlm.nih.gov/pubmed/22751438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21019
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