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Expression noise and acetylation profiles distinguishes HDACs functions

Gene expression shows a significant variation (noise) between genetically identical cells. Noise depends on the gene expression process regulated by the chromatin environment. We screened for chromatin factors that modulate noise in S. cerevisiae and analyzed the results using a theoretical model th...

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Detalhes bibliográficos
Main Authors: Weinberger, Leehee, Voichek, Yoav, Tirosh, Itay, Hornung, Gil, Amit, Ido, Barkai, Naama
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408861/
https://ncbi.nlm.nih.gov/pubmed/22683268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.008
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