RNA sequencing of pancreatic circulating tumour cells implicates WNT signaling in metastasis

Circulating tumour cells (CTCs) shed into blood from primary cancers include putative precursors that initiate distal metastases(1). While these cells are extraordinarily rare, they may identify cellular pathways contributing to the blood-borne dissemination of cancer. Here, we adapted a microfluidi...

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Auteurs principaux: Yu, Min, Ting, David T., Stott, Shannon L., Wittner, Ben S., Ozsolak, Fatih, Paul, Suchismita, Ciciliano, Jordan C., Smas, Malgorzata E., Winokur, Daniel, Gilman, Anna J., Ulman, Matthew J., Xega, Kristina, Contino, Gianmarco, Alagesan, Brinda, Brannigan, Brian W., Milos, Patrice M., Ryan, David P, Sequist, Lecia V., Bardeesy, Nabeel, Ramaswamy, Sridhar, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408856/
https://ncbi.nlm.nih.gov/pubmed/22763454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11217
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