Kinetics of the Oxidation of Reduced Cu,Zn-Superoxide Dismutase by Peroxymonocarbonate

Kinetic evidence is reported for the role of the peroxymonocarbonate, HOOCO(2)(−), as an oxidant for reduced Cu,Zn-superoxide dismutase-Cu(I) (SOD1) during the peroxidase activity of the enzyme. The formation of this reactive oxygen species results from the equilibrium between hydrogen peroxide and...

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Bibliographic Details
Main Authors:	Ranguelova, Kalina, Ganini, Douglas, Bonini, Marcelo G., London, Robert E., Mason, Ronald P.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3408790/ https://ncbi.nlm.nih.gov/pubmed/22569304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.04.029
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Kinetics of the Oxidation of Reduced Cu,Zn-Superoxide Dismutase by Peroxymonocarbonate

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