Sonic Hedgehog Maintains Cellular and Neurochemical Homeostasis in the Adult Nigrostriatal Circuit

Non cell-autonomous processes are thought to play critical roles in the cellular maintenance of the healthy and diseased brain but mechanistic details remain unclear. We report that the interruption of a non-cell autonomous mode of sonic hedgehog (Shh) signaling originating from dopaminergic neurons...

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Bibliographic Details
Main Authors: Gonzalez-Reyes, Luis E., Verbitsky, Miguel, Blesa, Javier, Jackson-Lewis, Vernice, Paredes, Daniel, Tillack, Karsten, Phani, Sudarshan, Kramer, Edgar R., Przedborski, Serge, Kottmann, Andreas H.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408586/
https://ncbi.nlm.nih.gov/pubmed/22841315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.05.018
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