Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex

Translational control of mRNAs in dendrites is essential for certain forms of synaptic plasticity and learning and memory. CPEB is an RNA-binding protein that regulates local translation in dendrites. Here, we identify poly(A) polymerase Gld2, deadenylase PARN, and translation inhibitory factor neur...

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Autori principali: Udagawa, Tsuyoshi, Swanger, Sharon A., Takeuchi, Koichi, Kim, Jong Heon, Nalavadi, Vijayalaxmi, Shin, Jihae, Lorenz, Lori J., Zukin, R. Suzanne, Bassell, Gary J., Richter, Joel D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408552/
https://ncbi.nlm.nih.gov/pubmed/22727665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.016
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