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p14ARF Post-Transcriptional Regulation of Nuclear Cyclin D1 in MCF-7 Breast Cancer Cells: Discrimination between a Good and Bad Prognosis?

As part of a cell’s inherent protection against carcinogenesis, p14ARF is upregulated in response to hyperproliferative signalling to induce cell cycle arrest. This property makes p14ARF a leading candidate for cancer therapy. This study explores the consequences of reactivating p14ARF in breast can...

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Detalhes bibliográficos
Main Authors: McGowan, Eileen M., Tran, Nham, Alling, Nikki, Yagoub, Daniel, Sedger, Lisa M., Martiniello-Wilks, Rosetta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408480/
https://ncbi.nlm.nih.gov/pubmed/22860097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042246
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