Dengue Virus Infection Mediates HMGB1 Release from Monocytes Involving PCAF Acetylase Complex and Induces Vascular Leakage in Endothelial Cells

High mobility group box 1 (HMGB1) protein is released from cells as a pro-inflammatory cytokine in response to an injury or infection. During dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS), a number of pro-inflammatory cytokines are released, contributing to disease pathogenesis. In this...

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Main Authors: Ong, Siew Pei, Lee, Ling Min, Leong, Yew Fai Ivan, Ng, Mah Lee, Chu, Justin Jang Hann
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408393/
https://ncbi.nlm.nih.gov/pubmed/22860034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041932
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