Tracing Determinants of Dual Substrate Specificity in Glycoside Hydrolase Family 5

Enzymes are traditionally viewed as having exquisite substrate specificity; however, recent evidence supports the notion that many enzymes have evolved activities against a range of substrates. The diversity of activities across glycoside hydrolase family 5 (GH5) suggests that this family of enzymes...

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Główni autorzy: Chen, Zhiwei, Friedland, Gregory D., Pereira, Jose H., Reveco, Sonia A., Chan, Rosa, Park, Joshua I., Thelen, Michael P., Adams, Paul D., Arkin, Adam P., Keasling, Jay D., Blanch, Harvey W., Simmons, Blake A., Sale, Kenneth L., Chivian, Dylan, Chhabra, Swapnil R.
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2012
Hasła przedmiotowe:
Enzymology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408205/
https://ncbi.nlm.nih.gov/pubmed/22645145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362640
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