Tracing Determinants of Dual Substrate Specificity in Glycoside Hydrolase Family 5

Enzymes are traditionally viewed as having exquisite substrate specificity; however, recent evidence supports the notion that many enzymes have evolved activities against a range of substrates. The diversity of activities across glycoside hydrolase family 5 (GH5) suggests that this family of enzymes...

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Autori principali: Chen, Zhiwei, Friedland, Gregory D., Pereira, Jose H., Reveco, Sonia A., Chan, Rosa, Park, Joshua I., Thelen, Michael P., Adams, Paul D., Arkin, Adam P., Keasling, Jay D., Blanch, Harvey W., Simmons, Blake A., Sale, Kenneth L., Chivian, Dylan, Chhabra, Swapnil R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Enzymology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408205/
https://ncbi.nlm.nih.gov/pubmed/22645145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362640
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