Transcriptional Regulation of the Protocadherin β Cluster during Her-2 Protein-induced Mammary Tumorigenesis Results from Altered N-Glycan Branching

Changes in the levels of N-acetylglucosaminyltransferase V (GnT-V) can alter the function of several types of cell surface receptors and adhesion molecules by causing altered N-linked glycan branching. Using a her-2 mammary tumor mouse model, her-2 receptor signaling was down-regulated by GnT-V knoc...

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Hlavní autoři: Guo, Huabei, Nairn, Alison, dela Rosa, Mitche, Nagy, Tamas, Zhao, Shaying, Moremen, Kelley, Pierce, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408139/
https://ncbi.nlm.nih.gov/pubmed/22665489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369355
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