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Hippocampal protection in mice with an attenuated inflammatory monocyte response to acute CNS picornavirus infection

Neuronal injury during acute viral infection of the brain is associated with the development of persistent cognitive deficits and seizures in humans. In C57BL/6 mice acutely infected with the Theiler's murine encephalomyelitis virus, hippocampal CA1 neurons are injured by a rapid innate immune...

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Detalhes bibliográficos
Main Authors: Howe, Charles L., LaFrance-Corey, Reghann G., Sundsbak, Rhianna S., Sauer, Brian M., LaFrance, Stephanie J., Buenz, Eric J., Schmalstieg, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408132/
https://ncbi.nlm.nih.gov/pubmed/22848791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00545
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