Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy

An increase in cardiac workload, ultimately resulting in hypertrophy, generates oxidative stress and therefore requires the activation of both survival and growth signal pathways. Here, we wanted to characterize the regulators, targets and mechanistic roles of miR-142, a microRNA (miRNA) negatively...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sharma, Salil, Liu, Jing, Wei, Jianqin, Yuan, Huijun, Zhang, Taifang, Bishopric, Nanette H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: WILEY-VCH Verlag 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407949/
https://ncbi.nlm.nih.gov/pubmed/22367739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200234
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